FACTORS ASSOCIATED WITH UPTAKE OF ISONIAZID PREVENTIVE THERAPY FOR TUBERCULOSIS AMONG HIV POSITIVE PATIENTS ACCESSING CARE FROM TASO MULAGO CENTER KAMPALA, UGANDA

Abstract

The study involved HIV positive patients who had been accessing care for the past three years from TASO Mulago Center Kampala, Uganda. The study objective was to determine the factors associated with Uptake of Isoniazid Preventive Therapy. The study sample size was 364 patients sampled from a target population of 7053 clients accessing care from TASO Mulago Center. It was a cross sectional study employing both quantitative and qualitative approaches. Data from the study was analyzed using descriptive statistics to obtain means, frequencies and standard deviations as well as inferential statistics to derive crude odds ratios and significances using binary logistic regression and multivariate analysis to obtain adjusted odds ratios. Results showed that majority of the respondents were females, most of the respondents were aged 31-40 years and primary was the highest education level attained by respondents. Only 11.26% of the respondents had knowledge about IPT, 16.5% received IPT related health education at the clinic, 47.4% have heard about latent TB infection from the community. However, majority (94.2%) feared acquiring TB, 92.3% disclosed their HIV status with 75.6% disclosing to family members. Health education and creating awareness about latent TB infection in the community were the only significant factors associated with uptake of IPT (AOR = 0.174, 95% CI = 0.055-0.548, p = 0.003) and (AOR = 7.494, 95% CI = 1.598-35.148, p = 0.011) respectively. Therefore, there is need for health care providers to incorporate IPT related health education at the clinic as well as creating awareness on latent TB infections in the community.