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Item Role of Lifestyle Risk Factors for Azoospermia: Insights from Ebenezer Clinical Laboratory - Kampala Capital City, Uganda(2025-04-25) Nuwagaba, Topha et alAzoospermia is one of the social problems affecting families/countries today in the whole world, which has resulted in an involuntary declining birth rate [1]. Worldwide, more than 70 million couples suffer from infertility, and it is estimated that azoospermia is found in up to 10 to 20 percent of the men who present to an infertility clinic [2]. Uganda is among the countries where male infertility is assumed to be a big challenge, with an estimated 5,000,000 people facinginfertility, where 10 to 15% of the couples are unable to have children. Hence the current study aimed at establishing the risk factors associated with azoospermia among patients attending Ebenezer Clinical Laboratory, Kampala, UgandaItem Therapeutic Potential of Brassica carinata Microgreens Extract in Alleviating Symptoms of Type 2 Diabetes in Wistar Rats(2024-11-16) Nakakaawa, Lilian et alMicrogreens of Brassica plants have attracted increasing research interest in the management of the prevailing epidemic of Type 2 diabetes mellitus (T2DM) because of their high nutritional value. This study evaluated the antidiabetic effects of Brassica car inata Microgreens Ethanolic Extract (BMEE) in type-2 diabetic rats. For the normoglycemic assay, rats were divided into five groups and received a single oral dose of 100, 250, and 500mg/kg of BMEE while the control groups received distilled water and Glibenclamide. Fasting blood glucose (FBG) levels were determined on a weekly basis for 28days in diabetic rats after treatment with BMEE at 250 and 500mg/kg dosage levels. Oral glucose tolerance test (OGTT), serum insulin levels, lipid profile and mes senger RNA expression levels of Insulin receptor substrate 1 (IRS-1), Glucose transporter 2 (GLUT2), and Nuclear factor kappa light-chain enhancer of activated B cells (NFKβ) genes were determined. BMEE did not induce hypoglycemic effects in rats with normal blood glucose levels, but induced antidiabetic activities in the experimental type-2 diabetic rats. BMEE lowered FBG levels, increased oral glucose tolerance, increased insulin sensitization, and reduced insulin resistance. Treatment of diabetic rats with BMEE increased lipid metabolism and relatively higher expression levels of IRS-1 and GLUT2 genes, and led to reduced expression levels of NFKβ in the liver. Overall, this study reports that BMEE has potential as a nutraceutical to be utilized in the management of T2DMItem Medical Related Determinants of Azoospermia Among Patients Attending Ebenezer Clinical Laboratory-Kampala Capital City, Uganda(International Journal of Advanced Multidisciplinary Research, 2024) Kizza, Stehen S et alOne of the societal issues plaguing families and nations now throughout the world is azoospermia, which has caused an unintentional decline in the birth rate (Sengoku, 2012). More than 70 million couples experience infertility globally, and up to 10–20 percent of males who visit an infertility clinic are thought to have azoospermia (Kumar, 2015). With an estimated 5,000,000 people experiencing infertility and 10 to 15% of couples failing to conceive, Uganda is among the nations where male infertility is thought to be a significant problem. Therefore, the goal of the study was to identify the medical-related determinants associated with azoospermia in patients who visit Ebenezer Clinical Laboratory in Kampala, Uganda.Item Prevalence of Non-Communicable Chronic Morbidities (NCCMs) and Associated Factors Among Persons Aged 60 Years And Above in Bulambuli District, Eastern Uganda Wanziima James G¹, Ndungutse David M2, Ndobooli Freddrick1 and Christopher Ddamulira1*(2024-04-17) Wanzima, James etalThe epidemiology of Non-Communicable Chronic Morbidities (NCCMs) is crucial in informing prevention and control initiatives for health systems in the developing world to handle the extra disease burden common in the aging population. Unfortunately, such evidence on the NCCMs and the associated factors remains scarce in Uganda and in Bugisu Sub-Region in particular just like in the rest of the Sub-Saharan Africa. Therefore, against this background, a study was undertaken to establish the prevalence of NCCMs and its associated factors among the elderly persons aged 60 years and above in Bulambuli District, Eastern Uganda.